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Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Biphenyl Moiety

Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate  Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine  Scaffold: SAR of the Biphenyl Moiety

PDF) Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia

Full article: The emergence of dihydroorotate dehydrogenase (DHODH) as a therapeutic target in acute myeloid leukemia

MEDS433 becomes highly effective also in partially resistant cell lines

PDF) Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia

PDF) Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a ]pyridine Scaffold: SAR of the Aryloxyaryl Moiety

DD1 is a Proteasome Inhibitor Used for Acute Myeloid Leukemia (AML) Research

Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3. - Abstract - Europe PMC

Compounds involved in the SAR exploration.

Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3. - Abstract - Europe PMC

Biochemical characterization of Mycobacterium tuberculosis dihydroorotate dehydrogenase and identification of a selective inhibitor - Alberti - 2023 - FEBS Letters - Wiley Online Library

Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Biphenyl Moiety

PDF) Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia

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